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Prefrontal cortical hemodynamic change due to facial expression switching task in autism spectrum disorders
https://bunkyo.repo.nii.ac.jp/records/6523
https://bunkyo.repo.nii.ac.jp/records/652336040f69-d964-4832-9378-037d9f015e66
Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2014-02-22 | |||||
タイトル | ||||||
タイトル | Prefrontal cortical hemodynamic change due to facial expression switching task in autism spectrum disorders | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | autism spectrum disorder | |||||
キーワード | ||||||
主題 | dorsolateral prefrontal cortex | |||||
キーワード | ||||||
主題 | near-infrared spectroscopy | |||||
キーワード | ||||||
主題 | facial expression switching task | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
著者 |
Higuchi, Hiroki
× Higuchi, Hiroki× Narita, Masaski× Sakatani, Kaoru× Narita, Naoko |
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所属機関 | ||||||
Kansei, Behavioral and Brain Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba | ||||||
所属機関 | ||||||
Developmental and Regenerative Medicine, Mie University | ||||||
所属機関 | ||||||
Department of Neurosurgery Nihon University School of Medicine | ||||||
所属機関 | ||||||
Institute of education, Bunkyo University | ||||||
内容記述 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Recent advances in functional neuroimaging studies disclosed different and/or defective signal processing system in reading emotion in autism spectrum disorder (ASD). In addition, we reported delayed or altered response of dorsolateral prefrontal cortex to incoming stimuli in ASD patients. In present study, we measure DLPFC cerebral blood oxygenation (CBO) changes during facial expression switching task to further examine neurofunctional characteristics of ASD. Five ASD patients (IQ>70,14-46 years, 2 females) and 22 healthy volunteers (19-38years, 12 females) participated in this study. The tasks required working memory and the tasks did not require WM are presented repeatedly, and number of presented stimulus are increased up to six. In healthy controls, activation pattern was relevant with task performance rate in the switching task using facial expression, on the other hands, this tendency was not shown in ASD patients. In one ASD patient, CBO changes in channel-35 that are mainly matched to fusiform gyrus were largely increased during geometric shapes switching task, however, similar pattern was not shown in facial expression switching task. These results imply DLPFC reactivity change according to task switch might be impaired in ASD patients due to ectopic functional connectivity. | |||||
書誌情報 |
SHONAN JOURNAL : The International Journal of the Shonan Research Institute Bunkyo University 巻 3, p. 41-55, 発行日 2012-03-01 |
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ISSN | ||||||
収録物識別子 | 21850178 | |||||
ISBN | ||||||
本文言語 | ||||||
英語 | ||||||
ID | ||||||
BKSS030007 | ||||||
作成日 | ||||||
日付 | 2014-02-21 |